High-level azithromycin-resistant Neisseria gonorrhoeae clinical isolate in France, March 2014.

نویسندگان

  • B Bercot
  • A Belkacem
  • A Goubard
  • F Mougari
  • P Sednaoui
  • G La Ruche
  • E Cambau
چکیده

We report the first case in France of a high-level azithromycin-resistant Neisseria gonorrhoeae (minimum inhibitory concentration (MIC) = 96 mg/L) assigned to MLST7363 (NG-MAST ST6360), also resistant to ciprofloxacin and tetracycline but susceptible to ceftriaxone. The patient was a 51 year-old heterosexual man who returned following 1g azithromycin monotherapy. Mechanisms of azithromycin resistance were a C2599T mutation in the four copies of the rrl gene and a novel mutation in the promoter of the mtrR gene.

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عنوان ژورنال:
  • Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

دوره 19 44  شماره 

صفحات  -

تاریخ انتشار 2014